The student goals of this one-term course are to:
- Explore the study of heredity across species
- Become proficient in the practice and interpretation of classical genetic analysis
- Connect classical genetic studies with modern genomic approaches
- The Central Question: What's up with DNA? Some history -
- Genetics was initially a study of traits that are passed from generation to generation.
- Farmers and breeders were really the first geneticists. Why do you think so?
- Mendel's studies led to a curiosity about the basis for inheritance.
- Modern genetic analysis emerged years later with Morgan's studies of flies.
- Modern understanding of gene expression emerged with Jacob and Monod's work.
- The Human Genome project promises to identify the genetic basis for many diseases.
How we will study this subject:
- Classroom Instruction
- Classical analysis techniques: Punnett squares, Probabilities
- Chromosomes and heredity I: Linkage and Epistasis
- Chromosomes and heredity II: Genetic Diseases, Pedigrees
- Molecular basis of heredity: DNA and Gene expression, The Central Dogma
- Human Genomics: Approaches and Implications, Ethics
Laboratory Studies/Field work: Trip To DNA Learning Center West at Cold Spring Harbor
- Individual students will analyze their own DNA on a one-day trip to CSH!
- Lab reports will involve analysis of student data and use of NIH databases.
: Successful completion of Modern Living Environment
or equivalents, Biology/LE Regents Proficiency. Genetics Research is open to sophomores, juniors and seniors in the fall term only.
Fulfillment of Requirements: Genetics Research is a prerequisite and/or co-requisite for AP Biology.
Grading Policy and Assessments: 70% Exams including cumulative final, 20% Lab reports and Homework assignments, 10% Daily oral class participation and In-class assessments.